Hoffman began stunt work in the 1970s with the film Two-Minute Warning, and several television series, including Police Story, and M*A*S*H. She performed a 78-foot high fall into water for The Love Boat, and did some work on Fantasy Island and Charlie's Angels. Leslie also doubled for the six-foot tall Lainie Kazan in a circular stair fall for Columbo. She even stunt doubled for Doris Roberts in the TV series Remington Steele. Her film acting work includes Avalanche, Deadly Friend, Trust Me, and Naked Gun.
Hoffman played the Hall Guard (Krueger) in Nightmare on Elm Street, and performed stunt work in I Wanna Hold Your Hand, Motel Hell, Resurrection, Clue, Alien Nation, Mars, and Mystery Men. She served as stunt coordinator for, and acted in, the ABC After School Special Me and My Hormones. She performed as the stunt-double for Laurie Metcalf in Scream 2.
From 1990's onward, she worked as a stunt coordinator and rigger on several films, as well as continuing to double for several actresses in feature films and television. Her work includes stunt acting roles in multiple episodes of the Star Trek: Voyager and Star Trek: Deep Space Nine television series.